Aplastic Anemia Clinical Trials

Not all trials are listed on www.ClinicalTrials.gov. The investigators may have chosen not to register the trial, or the study may not be eligible to be listed on ClinicalTrials.gov. If the study has not, for example, been approved by a human subject review board, it cannot be posted. Some trials are not listed because the investigators are not planning to publish the research findings, so you can ask the study coordinator why the study has not been included on ClinicalTrials.gov before you give your consent to participate.

The information on the studies linked below is provided strictly as a resource, not as an endorsement of any given treatment, doctor, or medical center.

Remember, before you sign a consent form, Clinical Trials Explained can help you understand the potential risks and benefits of a clinical trial. You can also contact the AA&MDSIF staff to discuss any questions you have at clinicaltrials@aamds.org or by calling the office at 301.279.7202 or 800.747.2820.

^{Last Modified: February 2009}

Bone Marrow Transplant Clinical Trials Network

Fludarabine-based Conditioning for Allogenic Marrow Transplantation From HLA-compatible Unrelated Donors in Severe Aplastic Anemia

Protocol BMT CTN 0301 | Multiple Locations

This is a phase I/II trial using fludarabine, cyclophosphamide, total body irradiation, and ant-thymocyte globulin (ATG) to evaluate the efficacy of fludarabine and lower the dose of cyclophospahmide in patients with severe aplastic anemia who require an unrelated donor bone marrow transplant. The addition of fludarabine should improve engraftment and lowering the dose of cyclophosphamide may reduce transplant-related complications thereby improving survival. Eligible patients must have a suitable matched unrelated donor, be less than 65 years of age and have severe aplastic anemia. Contact Dr. Paolo Anderlini, Principal Investigator at panderli@mdanderson.org. For more information about this protocol, eligibility criteria, and a list of locations, visit http://spitfire.emmes.com/. Also visit http://clinicaltrials.gov/ct/show/NCT00326417?order=1.

For patients with: AA

Link: https://web.emmes.com/study/bmt/protocol/0301_protocol/0301_protocol.html

Updated: December 11, 2007

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