Recent Research Information on Aplastic Anemia, MDS, and PNH

AA&MDSIF strives to keep patients, families, and hematology/oncology professionals up-to-date with developments in research and practice relevant to aplastic anemia, MDS and PNH. Shown below are recent articles from major hematology/oncology journals, retrieved from the National Library of Medicine’s PubMed portal to their MEDLINE database of journal citations and abstracts of the biomedical literature from around the world.

Looking for research oriented for patients and caregivers? For select reviews of important medical journal articles, written by hematology/oncology professionals, visit Research Reviews for Patients. These reviews interpret the most relevant information for patients from the latest published research.

You can also read Research Summaries for Patients that are lay language explanations of scientific meetings and symposia.

Summary information is listed by publication date, title, journal title and senior author. By default, the articles are listed by their publication date in reverse chronological order, from the most recent article to oldest article. Clicking the date column heading will sort them the other way, from oldest to newest.

"Publication date" in most cases means when the article first appeared in the electronic/online issue of a journal, in advance of when it appears in the print journal. Keep in mind some articles may appear online months before appearing in print, and that some may be from online-only journals.

You can also alphabetically and reverse alphabetically sort articles, primary authors and journal titles by clicking their column heading. To find articles by disease type, choose it from the drop-down menu named "Filter by Disease", and only articles about those diseases will appear. The search box labeled “Filter by Search Term” lets you search for a word in the article title, author, or journal name.

When you open an article citation by clicking on the title, article summary information (this time including all authors) is again shown, and in most cases you can view the article abstract. In some cases the abstract is unavailable, and not shown. You can also progress to the article’s PubMed entry by clicking the PubMed ID number link, shown directly under the title. Here you can purchase the article for download viewing or view through your institutional library’s access. In some cases, full text viewing is free either from the publisher’s site or from PubMed Central, an searchable aggregation site of free full text articles.

The PubMed Web site has extensive features, along with help tools and links to other databases. Regular users are encouraged to become familiar with its many capabilities.

Publication Date Article Title Journal Title Primary Author Bone Marrow Disease(s)
06/29/2015 Second allogeneic hematopoietic stem cell transplantation in children with severe aplastic anemia Bone Marrow Transplant Kudo K aplastic anemia
06/18/2015 CSNK1A1 mutations and gene expression analysis in myelodysplastic syndromes with del(5q). Br J Haematol Bello E myelodysplastic syndromes (MDS)
06/16/2015 Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria Blood Lin Z paroxysmal nocturnal hemoglobinuria (PNH)
06/12/2015 Accuracy of physician assessment of treatment preferences and health status in elderly patients with higher-risk myelodysplastic syndromes Leuk Res Caocci G myelodysplastic syndromes (MDS)
06/01/2015 Paroxysmal Nocturnal Hemoglobinuria: A Complement-Mediated Hemolytic Anemia Hematol Oncol Clin North Am DeZern AE paroxysmal nocturnal hemoglobinuria (PNH)
05/31/2015 Myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms: an update on risk stratification, molecular genetics, and therapeutic approaches including allogeneic hematopoietic stem cell transplantation Am Soc Clin Oncol Educ Book Odenike O myelodysplastic syndromes (MDS)
05/26/2015 Molecular pathology of myelodysplastic syndromes: new developments and implications for diagnosis and treatment Leuk Lymphoma Zhang X myelodysplastic syndromes (MDS)
05/25/2015 Albumin as a prognostic marker in myelodysplastic syndromes: still relevant after all these years Leuk Lymphoma Gerds AT myelodysplastic syndromes (MDS)
05/16/2015 Successful pregnancy outcome in paroxysmal nocturnal hemoglobinuria (PNH) following escalated eculizumab dosing to control breakthrough hemolysis Leuk Res Rep Sharma R paroxysmal nocturnal hemoglobinuria (PNH)
05/08/2015 TP53 mutation characteristics in therapy-related myelodysplastic syndromes and acute myeloid leukemia is similar to de novo diseases J Hematol Oncol Ok CY myelodysplastic syndromes (MDS)