Recent Research Information on Aplastic Anemia, MDS, and PNH

AA&MDSIF strives to keep patients, families, and hematology/oncology professionals up-to-date with developments in research and practice relevant to aplastic anemia, MDS and PNH. Shown below are recent articles from major hematology/oncology journals, retrieved from the National Library of Medicine’s PubMed portal to their MEDLINE database of journal citations and abstracts of the biomedical literature from around the world.

Looking for research oriented for patients and caregivers? For select reviews of important medical journal articles, written by hematology/oncology professionals, visit Research Reviews for Patients. These reviews interpret the most relevant information for patients from the latest published research.

You can also read Research Summaries for Patients that are lay language explanations of scientific meetings and symposia.

Summary information is listed by publication date, title, journal title and senior author. By default, the articles are listed by their publication date in reverse chronological order, from the most recent article to oldest article. Clicking the date column heading will sort them the other way, from oldest to newest.

"Publication date" in most cases means when the article first appeared in the electronic/online issue of a journal, in advance of when it appears in the print journal. Keep in mind some articles may appear online months before appearing in print, and that some may be from online-only journals.

You can also alphabetically and reverse alphabetically sort articles, primary authors and journal titles by clicking their column heading. To find articles by disease type, choose it from the drop-down menu named "Filter by Disease", and only articles about those diseases will appear. The search box labeled “Filter by Search Term” lets you search for a word in the article title, author, or journal name.

When you open an article citation by clicking on the title, article summary information (this time including all authors) is again shown, and in most cases you can view the article abstract. In some cases the abstract is unavailable, and not shown. You can also progress to the article’s PubMed entry by clicking the PubMed ID number link, shown directly under the title. Here you can purchase the article for download viewing or view through your institutional library’s access. In some cases, full text viewing is free either from the publisher’s site or from PubMed Central, an searchable aggregation site of free full text articles.

The PubMed Web site has extensive features, along with help tools and links to other databases. Regular users are encouraged to become familiar with its many capabilities.

Publication Date Article Title Journal Title Primary Author Bone Marrow Disease(s)
12/01/2014 Mesenchymal stromal cell density is increased in higher grade myelodysplastic syndromes and independently predicts survival Am J Clin Pathol Johnson RC myelodysplastic syndromes (MDS)
10/30/2014 GATA2 deficiency-associated bone marrow disorder differs from idiopathic aplastic anemia Blood Ganapathi KA aplastic anemia
10/30/2014 Cyclophosphamide in severe aplastic anemia? Blood Peffault de Latour R aplastic anemia
10/23/2014 MDS-related mutations in aplastic anemia Blood Ogawa S aplastic anemia
10/21/2014 Hematopoietic stem cell transplantation for aplastic anemia and paroxysmal nocturnal hemoglobinuria: current evidence and recommendations Expert Rev Hematol Marotta S aplastic anemia, paroxysmal nocturnal hemoglobinuria (PNH)
10/11/2014 Long-term Survival and Late Effects among 1-year Survivors of Second Allogeneic Hematopoietic Cell Transplantation for Relapsed Acute Leukemia and Myelodysplastic Syndromes Biol Blood Marrow Transplant Duncan CN myelodysplastic syndromes (MDS)
10/01/2014 Prevalence, severity and correlates of fatigue in newly diagnosed patients with myelodysplastic syndromes Br J Haematol Efficace F myelodysplastic syndromes (MDS)
10/01/2014 Stem cell transplants for myelodysplastic syndromes: refining the outcome predictions Haematologica Barrett AJ myelodysplastic syndromes (MDS)
09/27/2014 Lack of objective response of myelodysplastic syndromes and acute myeloid leukemia to decitabine after failure of azacitidine Leuk Lymphoma Duong VH myelodysplastic syndromes (MDS)
09/19/2014 Genomic analysis of bone marrow failure and myelodysplastic syndromes reveals phenotypic and diagnostic complexity Haematologica Zhang MY myelodysplastic syndromes (MDS)