Recent Research Information on Aplastic Anemia, MDS, and PNH

AA&MDSIF strives to keep patients, families, and hematology/oncology professionals up-to-date with developments in research and practice relevant to aplastic anemia, MDS and PNH. Shown below are recent articles from major hematology/oncology journals, retrieved from the National Library of Medicine’s PubMed portal to their MEDLINE database of journal citations and abstracts of the biomedical literature from around the world.

Looking for research oriented for patients and caregivers? For select reviews of important medical journal articles, written by hematology/oncology professionals, visit Research Reviews for Patients. These reviews interpret the most relevant information for patients from the latest published research.

You can also read Research Summaries for Patients that are lay language explanations of scientific meetings and symposia.

Summary information is listed by publication date, title, journal title and senior author. By default, the articles are listed by their publication date in reverse chronological order, from the most recent article to oldest article. Clicking the date column heading will sort them the other way, from oldest to newest.

"Publication date" in most cases means when the article first appeared in the electronic/online issue of a journal, in advance of when it appears in the print journal. Keep in mind some articles may appear online months before appearing in print, and that some may be from online-only journals.

You can also alphabetically and reverse alphabetically sort articles, primary authors and journal titles by clicking their column heading. To find articles by disease type, choose it from the drop-down menu named "Filter by Disease", and only articles about those diseases will appear. The search box labeled “Filter by Search Term” lets you search for a word in the article title, author, or journal name.

When you open an article citation by clicking on the title, article summary information (this time including all authors) is again shown, and in most cases you can view the article abstract. In some cases the abstract is unavailable, and not shown. You can also progress to the article’s PubMed entry by clicking the PubMed ID number link, shown directly under the title. Here you can purchase the article for download viewing or view through your institutional library’s access. In some cases, full text viewing is free either from the publisher’s site or from PubMed Central, an searchable aggregation site of free full text articles.

The PubMed Web site has extensive features, along with help tools and links to other databases. Regular users are encouraged to become familiar with its many capabilities.

Publication Date Article Title Journal Title Primary Author Bone Marrow Disease(s)
03/20/2014 Eltrombopag in refractory severe aplastic anemia Blood No authors listed aplastic anemia
03/20/2014 Myelodysplastic syndromes Lancet Adès L myelodysplastic syndromes (MDS)
03/20/2014 Multicenter study evaluating the impact of hypomethylating agents as bridging therapy to hematopoietic stem cell transplantation in myelodysplastic syndromes Int J Hematol Kim Y myelodysplastic syndromes (MDS)
03/18/2014 Fishing for myelodysplastic syndromes finds uncaptured cases by state cancer registries: Need for more resources Cancer Cogle CR myelodysplastic syndromes (MDS)
03/18/2014 Toward resolving the unsettled role of iron chelation therapy in myelodysplastic syndromes Expert Rev Anticancer Ther Merkel DG myelodysplastic syndromes (MDS)
03/12/2014 Impaired proliferative potential of bone marrow mesenchymal stem cells in patients with myelodysplastic syndromes is associated with abnormal WNT signaling pathway Stem Cells Dev Pavlaki K myelodysplastic syndromes (MDS)
03/03/2014 Reduced intensity conditioning, combined transplantation of haploidentical hematopoietic stem cells and mesenchymal stem cells in patients with severe aplastic anemia PLoS One Li XH aplastic anemia
03/01/2014 Cytogenetics in benzene-associated myelodysplastic syndromes and acute myeloid leukemia: new insights into a disease continuum Ann N Y Acad Sci Irons RD myelodysplastic syndromes (MDS)
03/01/2014 Risk for developing myelodysplastic syndromes in prostate cancer patients definitively treated with radiation J Natl Cancer Inst Mukherjee S myelodysplastic syndromes (MDS)
03/01/2014 Radiation alone for solid tumors and the questionable development of therapy-related myelodysplastic syndromes J Natl Cancer Inst Cogle CR myelodysplastic syndromes (MDS)