Recent Research Information on Aplastic Anemia, MDS, and PNH

AA&MDSIF strives to keep patients, families, and hematology/oncology professionals up-to-date with developments in research and practice relevant to aplastic anemia, MDS and PNH. Shown below are recent articles from major hematology/oncology journals, retrieved from the National Library of Medicine’s PubMed portal to their MEDLINE database of journal citations and abstracts of the biomedical literature from around the world.

Looking for research oriented for patients and caregivers? For select reviews of important medical journal articles, written by hematology/oncology professionals, visit Research Reviews for Patients. These reviews interpret the most relevant information for patients from the latest published research.

You can also read Research Summaries for Patients that are lay language explanations of scientific meetings and symposia.

Summary information is listed by publication date, title, journal title and senior author. By default, the articles are listed by their publication date in reverse chronological order, from the most recent article to oldest article. Clicking the date column heading will sort them the other way, from oldest to newest.

"Publication date" in most cases means when the article first appeared in the electronic/online issue of a journal, in advance of when it appears in the print journal. Keep in mind some articles may appear online months before appearing in print, and that some may be from online-only journals.

You can also alphabetically and reverse alphabetically sort articles, primary authors and journal titles by clicking their column heading. To find articles by disease type, choose it from the drop-down menu named "Filter by Disease", and only articles about those diseases will appear. The search box labeled “Filter by Search Term” lets you search for a word in the article title, author, or journal name.

When you open an article citation by clicking on the title, article summary information (this time including all authors) is again shown, and in most cases you can view the article abstract. In some cases the abstract is unavailable, and not shown. You can also progress to the article’s PubMed entry by clicking the PubMed ID number link, shown directly under the title. Here you can purchase the article for download viewing or view through your institutional library’s access. In some cases, full text viewing is free either from the publisher’s site or from PubMed Central, an searchable aggregation site of free full text articles.

The PubMed Web site has extensive features, along with help tools and links to other databases. Regular users are encouraged to become familiar with its many capabilities.

Publication Date Article Title Journal Title Primary Author Bone Marrow Disease(s)
01/01/2015 The molecular basis and clinical significance of genetic mutations identified in myelodysplastic syndromes Leuk Res Zhang L myelodysplastic syndromes (MDS)
01/01/2015 Aplastic Anemia & MDS International Foundation: Bone Marrow Failure Disease Scientific Symposium 2014 Leuk Res Visconte V paroxysmal nocturnal hemoglobinuria (PNH)
12/24/2014 Matched sibling donor hematopoietic stem cell transplant in patients with acquired aplastic anemia Curr Drug Targets Tichelli A aplastic anemia
12/23/2014 Pathogenesis of myelodysplastic syndromes: an overview of molecular and non-molecular aspects of the disease Blood Res Visconte V myelodysplastic syndromes (MDS)
12/15/2014 Bone Marrow Transplantation for Acquired Severe Aplastic Anemia Hematol Oncol Clin North Am Bacigalupo A aplastic anemia
12/15/2014 Transplants in Myelodysplastic Syndromes Hematol Oncol Clin North Am. Wetzko K myelodysplastic syndromes (MDS)
12/15/2014 Improved risk stratification by the integration of the revised International Prognostic Scoring System with the Myelodysplastic Syndromes Comorbidity Index Eur J Cancer van Spronsen MF myelodysplastic syndromes (MDS)
12/05/2014 A Phase 1 Study of Oral ARRY-614, a p38 MAPK/Tie2 Dual Inhibitor, in Patients with Low or Intermediate 1 Risk Myelodysplastic Syndromes Clin Cancer Res Garcia-Manero G myelodysplastic syndromes (MDS)
12/04/2014 Assessing complement blockade in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab Blood Peffault de Latour R paroxysmal nocturnal hemoglobinuria (PNH)
12/04/2014 Multiparameter FLAER-based flow cytometry for screening of paroxysmal nocturnal hemoglobinuria enhances detection rates in patients with aplastic anemia Ann Hematol Sachdeva MU aplastic anemia