Recent Research Information on Aplastic Anemia, MDS, and PNH

AA&MDSIF strives to keep patients, families, and hematology/oncology professionals up-to-date with developments in research and practice relevant to aplastic anemia, MDS and PNH. Shown below are recent articles from major hematology/oncology journals, retrieved from the National Library of Medicine’s PubMed portal to their MEDLINE database of journal citations and abstracts of the biomedical literature from around the world.

Looking for research oriented for patients and caregivers? For select reviews of important medical journal articles, written by hematology/oncology professionals, visit Research Reviews for Patients. These reviews interpret the most relevant information for patients from the latest published research.

You can also read Research Summaries for Patients that are lay language explanations of scientific meetings and symposia.

Summary information is listed by publication date, title, journal title and senior author. By default, the articles are listed by their publication date in reverse chronological order, from the most recent article to oldest article. Clicking the date column heading will sort them the other way, from oldest to newest.

"Publication date" in most cases means when the article first appeared in the electronic/online issue of a journal, in advance of when it appears in the print journal. Keep in mind some articles may appear online months before appearing in print, and that some may be from online-only journals.

You can also alphabetically and reverse alphabetically sort articles, primary authors and journal titles by clicking their column heading. To find articles by disease type, choose it from the drop-down menu named "Filter by Disease", and only articles about those diseases will appear. The search box labeled “Filter by Search Term” lets you search for a word in the article title, author, or journal name.

When you open an article citation by clicking on the title, article summary information (this time including all authors) is again shown, and in most cases you can view the article abstract. In some cases the abstract is unavailable, and not shown. You can also progress to the article’s PubMed entry by clicking the PubMed ID number link, shown directly under the title. Here you can purchase the article for download viewing or view through your institutional library’s access. In some cases, full text viewing is free either from the publisher’s site or from PubMed Central, an searchable aggregation site of free full text articles.

The PubMed Web site has extensive features, along with help tools and links to other databases. Regular users are encouraged to become familiar with its many capabilities.

Publication Date Article Title Journal Title Primary Author Bone Marrow Disease(s)
06/27/2014 Response to azacitidine is independent of p53 expression in higher-risk myelodysplastic syndromes and secondary acute myeloid leukemia. Haematologica Müller-Thomas C myelodysplastic syndromes (MDS)
06/23/2014 Patients with Myelodysplastic Syndromes Treated with Azacitidine in Clinical Practice: The AVIDA® Registry Leuk Lymphoma Grinblatt DL myelodysplastic syndromes (MDS)
06/06/2014 Genetic characterization of acquired aplastic anemia by targeted sequencing Haematologica Heuser M aplastic anemia
06/06/2014 In vivo effects of horse and rabbit antithymocyte globulin in patients with severe aplastic anemia Haematologica Feng X aplastic anemia
06/05/2014 Outcome of Allogeneic Stem Cell Transplantation for Patients Transformed to MDS or Leukemia from Severe Aplastic Anemia. A report by the MDS subcommittee of the chronic malignancies working party (CMWP) and the severe aplastic anemia working party (WPSAA) Biol Blood Marrow Transplant Hussein AA aplastic anemia
06/05/2014 Integrating genetics and epigenetics in myelodysplastic syndromes: advances in pathogenesis and disease evolution Br J Haematol Montalbán Bravo G myelodysplastic syndromes (MDS)
06/05/2014 Disease progression in myelodysplastic syndromes: do mesenchymal cells pave the way? Cell Stem Cell Raaijmakers MH myelodysplastic syndromes (MDS)
06/04/2014 The Challenging World of Cytopenias: Distinguishing Myelodysplastic Syndromes From Other Disorders of Marrow Failure Oncologist DeZern AE myelodysplastic syndromes (MDS)
06/01/2014 Clinical and genetic predictors of prognosis in myelodysplastic syndromes Haematologica Bejar R myelodysplastic syndromes (MDS)
06/01/2014 Prolonged cyclosporine administration after antithymocyte globulin delays but does not prevent relapse in severe aplastic anemia Am J Hematol Scheinberg P aplastic anemia