Recent Research Information on Aplastic Anemia, MDS, and PNH

AA&MDSIF strives to keep patients, families, and hematology/oncology professionals up-to-date with developments in research and practice relevant to aplastic anemia, MDS and PNH. Shown below are recent articles from major hematology/oncology journals, retrieved from the National Library of Medicine’s PubMed portal to their MEDLINE database of journal citations and abstracts of the biomedical literature from around the world.

Looking for research oriented for patients and caregivers? For select reviews of important medical journal articles, written by hematology/oncology professionals, visit Research Reviews for Patients. These reviews interpret the most relevant information for patients from the latest published research.

You can also read Research Summaries for Patients that are lay language explanations of scientific meetings and symposia.

Summary information is listed by publication date, title, journal title and senior author. By default, the articles are listed by their publication date in reverse chronological order, from the most recent article to oldest article. Clicking the date column heading will sort them the other way, from oldest to newest.

"Publication date" in most cases means when the article first appeared in the electronic/online issue of a journal, in advance of when it appears in the print journal. Keep in mind some articles may appear online months before appearing in print, and that some may be from online-only journals.

You can also alphabetically and reverse alphabetically sort articles, primary authors and journal titles by clicking their column heading. To find articles by disease type, choose it from the drop-down menu named "Filter by Disease", and only articles about those diseases will appear. The search box labeled “Filter by Search Term” lets you search for a word in the article title, author, or journal name.

When you open an article citation by clicking on the title, article summary information (this time including all authors) is again shown, and in most cases you can view the article abstract. In some cases the abstract is unavailable, and not shown. You can also progress to the article’s PubMed entry by clicking the PubMed ID number link, shown directly under the title. Here you can purchase the article for download viewing or view through your institutional library’s access. In some cases, full text viewing is free either from the publisher’s site or from PubMed Central, an searchable aggregation site of free full text articles.

The PubMed Web site has extensive features, along with help tools and links to other databases. Regular users are encouraged to become familiar with its many capabilities.

Publication Date Article Title Journal Title Primary Author Bone Marrow Disease(s)
02/01/2016 Myelodysplastic Syndromes and Acute Myeloid Leukemia in the Elderly Clin Geriatr Med Klepin HD myelodysplastic syndromes (MDS)
02/01/2016 Evolving hematopoietic stem cell transplantation strategies in severe aplastic anemia Curr Opin Pediatr Dietz AC aplastic anemia
01/25/2016 Lost in translation? Ten years of development of histone deacetylase inhibitors in acute myeloid leukemia and myelodysplastic syndromes Expert Opin Investig Drugs Stahl M myelodysplastic syndromes (MDS)
01/13/2016 Memory Stem T Cells in Autoimmune Disease: High Frequency of Circulating CD8+ Memory Stem Cells in Acquired Aplastic Anemia J Immunol Hosokawa K aplastic anemia
01/06/2016 Selectivity of C3-opsonin targeted complement inhibitors: A distinct advantage in the protection of erythrocytes from paroxysmal nocturnal hemoglobinuria patients Immunobiology Schmidt CQ paroxysmal nocturnal hemoglobinuria (PNH)
01/01/2016 Myelodysplastic syndromes: Contemporary review and how we treat Am J Hematol Gangat N myelodysplastic syndromes (MDS)
01/01/2016 Unraveling Myelodysplastic Syndromes: Current Knowledge and Future Directions Curr Oncol Rep Chamseddine AN myelodysplastic syndromes (MDS)
12/29/2015 Allogeneic stem cell transplantation in myelodysplastic syndromes: does pretransplant clonal burden matter? Curr Opin Hematol Brierley CK myelodysplastic syndromes (MDS)
12/23/2015 Prevalence, clinical characteristics and prognosis of GATA2-related myelodysplastic syndromes (MDS) in children and adolescents Blood Wlodarski MW myelodysplastic syndromes (MDS)
12/22/2015 Outcomes of patients with myelodysplastic syndromes who achieve stable disease after treatment with hypomethylating agents Leuk Res. Nazha A myelodysplastic syndromes (MDS)