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Outcomes of patients with hematologic malignancies and COVID-19: A systematic review and meta-analysis of 3377 patients

Key Points
Adult patients with hematologic malignancy and COVID-19 have a 34% risk of death, while pediatric patients have a 4% risk of death.

Patients on systemic anti-cancer therapy had a similar risk of death to patients on no treatment (RR 1.17, 95% CI 0.83-1.64).

Rogue Antibodies and Gene Mutations Explain Some Cases of Severe COVID-19

One of the many perplexing issues with COVID-19 is that it affects people so differently. That has researchers trying to explain why some folks bounce right back from the virus, or don’t even know they have it—while others become critically ill. Now, two NIH-funded studies suggest that one reason some otherwise healthy people become gravely ill may be previously unknown trouble spots in their immune systems, which hamper their ability to fight the virus.