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Tacrolimus
Tacrolimus:
Tacrolimus is in a class of medications called immunosuppressants. It works by decreasing the activity of the immune system. Tacrolimus can be prescribed to treat and prevent graft vs host disease (GVHD). It can also be used as part of combination therapy to treat aplastic anemia in place of…
is in a class of medications called immunosuppressants. It works by…
Drug last updated
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Hydroxyurea
Hydroxyurea:
Hydroxyurea is in a class of medications called antimetabolites. Hydroxyurea treats cancer by slowing or stopping the growth of cancer cells in your body. It can be used alone or with other medications to treat a certain types of leukemias.
is in a class of medications called antimetabolites. Hydroxyurea treats cancer by slowing or stopping the growth of…
Drug last updated
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A methylated derivative and structural analog of PRIMA-1 (p53 re-activation and induction of massive
apoptosis
apoptosis:
Programmed cell death.
), with potential antineoplastic activity. Upon administration, PRIMA-1 analog
APR-246
APR-246:
A methylated derivative and structural analog of PRIMA-1 (p53 re-activation and induction of massive apoptosis), with potential…
Drug last updated
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Folate
Folate:
(FOE-late) A B-vitamin that is found in fresh or lightly cooked green vegetables. It helps the bone marrow make normal blood cells. Most people get enough folate in their diet. Doctors may have people with paroxysmal nocturnal hemaglobinuria (PNH) take a man-made form of folate called folic acid.
is a B-vitamin that is found in fresh or lightly cooked green vegetables.…
Treatment last updated
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Clinical research
Clinical research:
A type of research that involves individual persons or a group of people. There are three types of clinical research. Patient-oriented research includes clinical trials which test how a drug, medical device, or treatment approach works in people. Epidemiology or behavioral studies look at the…
is at the heart of all medical advances, identifying new…
Treatment last updated
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Growth factors
Growth factors:
Growth factors are naturally occurring hormones in your body that signal your bone marrow to make more of certain types of blood cells. Man-made growth factors may be given to some people with bone marrow failure diseases to help increase red blood cell, white blood cell or platelet counts.
Red…
are naturally occurring hormones in your body that signal…
Treatment last updated
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Androgens
Androgens:
Androgens are natural male hormones that can cause your bone marrow to make more red blood cells. This can improve anemia. Androgens are sometimes used to treat aplastic anemia and PNH.
Androgens that may be used include:
Danazol (Danacrine®)
Fluoxymestrone (Halotestin®)
Oxymetholone
…
are natural male hormones that can cause your
bone marrow
bone…
Treatment last updated
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Iron chelation therapy
Iron chelation therapy:
(kee-LAY-shun) A drug therapy to remove extra iron from the body. Patients with high blood iron (ferritin) levels may receive iron chelation therapy. The U.S. Food and Drug Administratin (FDA) has approved two iron chelators to treat iron overload in the U.S. - deferasirox, an oral iron chelator,…
is the main treatment used when you have a…
Treatment last updated
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If you have MDS and have a high-risk or intermediate-2 risk IPSS score, you have a higher risk of developing
Acute Myelogenous Leukemia
Acute Myelogenous Leukemia:
(uh-KYOOT my-uh-LAH-juh-nuss loo-KEE-mee-uh) A cancer of the blood cells. It happens when very young white blood cells (blasts) in the bone marrow fail to mature. The blast cells stay in the bone marrow and become to numerous…
Treatment last updated
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Immunosuppressive drug therapy
Immunosuppressive drug therapy:
(i-myoo-no-suh-PREH-siv) Drugs that lower the body's immune response and allow the bone marrow stem cells to grow and make new blood cells. ATG (antithymocyte globulin) or ALG (antilymphocyte globulin) with cyclosporine are used to treat bone marrow failure in aplastic anemia. Immunosuppressive…
lowers your body's immune…
Treatment last updated
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Diseases like
aplastic anemia
aplastic anemia:
(ay-PLASS-tik uh-NEE_mee-uh) A rare and serious condition in which the bone marrow fails to make enough blood cells - red blood cells, white blood cells, and platelets. The term aplastic is a Greek word meaning not to form. Anemia is a condition that happens when red blood cell count is low. Most…
,
myelodysplastic syndromes…
Basic page last updated
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The most common white blood cells are called neutrophils. They fight infection. Patients who don't have enough healthy neutrophils are said to have
neutropenia
neutropenia:
(noo-truh-PEE-nee-uh) A condition in which there is a shortage of neutrophils in the bloodstream. Neutrophils are a type of white blood cell. This results in a low white blood cell count.
. Because of their low white…
Treatment last updated
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Dr. Lourdes Mendez explains High-Risk MDS, or
Myelodysplastic Syndromes
Myelodysplastic Syndromes:
(my-eh-lo-diss-PLASS-tik SIN-dromez) A group of disorders where the bone marrow does not work well, and the bone marrow cells fail to make enough healthy blood cells. Myelo refers to the bone marrow. Dysplastic means abnormal growth or development. People with MDS have low blood cell…
Webinar last updated
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Tiffany was putting her degree in psychology to work. A Bethune-Cookman University graduate, she was working her dream job in a facility in Jacksonville, Florida. Then the diagnosis of
Aplastic Anemia
Aplastic Anemia:
(ay-PLASS-tik uh-NEE_mee-uh) A rare and serious condition in which the bone marrow fails to make enough blood cells - red blood cells, white blood cells, and…
Patient Chronicle last updated
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Hello this is Sahar, a woman who fled her homeland followed by the failure of her
bone marrow
bone marrow:
The soft, spongy tissue inside most bones. Blood cells are formed in the bone marrow.
within 6 months. I am a daughter, a devoted wife, a mom to two adorable children. I am an Afghan refugee, but today I stand as a survivor- having battled
Aplastic Anemia
Aplastic Anemia…
Patient Chronicle last updated
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In this webinar, patients diagnosed with MDS discuss their patient journey and share their personal experiences.
Webinar last updated
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My husband David’s journey with MDS began in April 2014, when it was discovered almost by chance while we were on vacation. David was bitten by a brown recluse spider and had a very severe reaction to it. He had to be hospitalized, which is when he got his first blood test in years. The doctor noted that his blood counts were low and, while he didn’t rule out that the spider bite might have…
Patient Chronicle last updated
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At the age of 3, I became ill with a rare blood disorder. I was bruising easily, and my platelet count was dangerously low. I was diagnosed to have ITP, had my spleen removed, and thought I was cured. However, my disease was either dormant or morphing into something else. My symptoms recurred with pregnancy, and after my second child was born, my disease was never dormant again. In 1993…
Patient Chronicle last updated
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After Liviya’s diagnosis of severe
aplastic anemia
aplastic anemia:
(ay-PLASS-tik uh-NEE_mee-uh) A rare and serious condition in which the bone marrow fails to make enough blood cells - red blood cells, white blood cells, and platelets. The term aplastic is a Greek word meaning not to form. Anemia is a condition that happens when red blood cell count is low. Most…
, my wife Rebekah and…
Patient Chronicle last updated
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