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PNH is considered a chronic disease meaning that it lasts a long time. The only potential cure is a
bone marrow transplant (BMT)
bone marrow transplant (BMT):
A procedure where bone marrow stem cells are collected from marrow inside the donor's hipbone and given to the patient through an intravenous (IV) line. In time, donated stem cells start making new, healthy blood cells.
. However…
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(excerpted from Thomas’ Hematopoietic Stem Cell Transplantation, 5th Edition)
The first interface many patients have with an HCT transplant program occurs at the time they come for a second opinion. Often patients make a consultation appointment to compare a particular program with other centers they are considering. These patients meet with a transplant physician to review their options, a…
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The parts of blood used in a transfusion depend on why the patient needs the transfusion. The two types of transfusion typically used for
bone marrow failure
bone marrow failure:
A condition that occurs when the bone marrow stops making enough healthy blood cells. The most common of these rare diseases are aplastic anemia, myelodysplastic syndromes (MDS) and paroxysmal nocturnal…
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My husband Rick and I knew Jake was not feeling well. He kept denying it and saying he was fine. A bloody nose scared me, and then I remembered how my brother-in-law had them as a child and thought it was hereditary. Then his high school said he had another. He began to ask us if he looked pale. We said that he did. He also was coughing and seemed lethargic. We encouraged him to go to…
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What are Chronic Myeloproliferative Neoplasms or MPNs?
In myeloproliferative neoplasms (MPN), the
bone marrow
bone marrow:
The soft, spongy tissue inside most bones. Blood cells are formed in the bone marrow.
makes too many of one or more types of blood cells. Neoplasms usually get worse over time as the number of extra blood cells increases.
The six different types of MPN are…
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Negative side effects of blood transfusion therapy are uncommon. Blood banks, hospitals, and health-care providers take many precautions to minimize risks before each blood transfusion.
Blood banks test each unit of blood to find out its ABO type and Rh status. In the United States, after a hospital laboratory receives a blood unit from the blood bank, the laboratory tests the unit again.…
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What is Chronic Myelomonocytic Leukemia or CMML?
Chronic myelomonocytic leukemia (CMML) starts in the
bone marrow
bone marrow:
The soft, spongy tissue inside most bones. Blood cells are formed in the bone marrow.
and then moves to the blood. It happens when monocytes in the bone marrow begin to grow out of control, filling the bone marrow and preventing other blood cells from growing…
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Blood is made of blood cells floating in
plasma
plasma:
The fluid part of the blood. Plasma is mostly made of water with chemicals in it. These chemicals include proteins, hormones, minerals, and vitamins.
. The plasma is mostly made of water with chemicals in it. These chemicals include proteins, hormones, minerals and vitamins.
There are three basic types of blood cells. These…
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What is Pure Red Cell Aplasia or PRCA?
There are three types of PRCA:
Acquired Pure Red Cell Aplasia: This is a very rare condition and usually affects adults. It is characterized by an absence of red cell precursors (reticulocytes) in the marrow and a low
red blood cell
red blood cell:
The most numerous type of blood cell in healthy people. Red blood cells…
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The process of making blood cells is called
hematopoiesis
hematopoiesis:
(hi-mat-uh-poy-EE-suss) The process of making blood cells in the bone marrow.
. Blood cells are made in the
bone marrow
bone marrow:
The soft, spongy tissue inside most bones. Blood cells are formed in the bone marrow.
. That's a spongy tissue located inside some bones. It contains young parent cells…
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What is Acute Myeloid Leukemia or AML?
Acute myeloid leukemia
Acute myeloid leukemia:
(uh-KYOOT my-uh-LOYD loo-KEE-mee-uh) A cancer of the blood cells. It happens when very young white blood cells (blasts) in the bone marrow fail to mature. The blast cells stay in the bone marrow and become to numerous. This slows production of red blood cells and platelets. Some cases of MDS become…
(…
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When you have a low blood count, this means your bone marrow is not making enough of one type of blood cells. Doctors call a low blood count
cytopenia
cytopenia:
(sie-tuh-PEE-nee-uh) A shortage of one or more blood cell types. Also called a low blood count.
. You can have one or more low blood counts.
Doctors use an important blood test called a complete blood count,…
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How long do I have to live?
This is most people’s first question, along with “what can I expect to happen.” The doctor’s answer is called a prognosis (an educated guess about the likely course of your disease and how long you might live). Because each person is unique, and each person’s disease is different, a prognosis can be difficult to make. Also, how a disease progresses over time is…
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The symptoms of
bone marrow failure
bone marrow failure:
A condition that occurs when the bone marrow stops making enough healthy blood cells. The most common of these rare diseases are aplastic anemia, myelodysplastic syndromes (MDS) and paroxysmal nocturnal hemoglobinuria (PNH). Bone marrow failure can be acquired (begin any time in life) or can be…
diseases like
aplastic anemia…
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The Abramson Cancer Center at Penn Medicine holds a
bone marrow transplant
bone marrow transplant:
A bone marrow transplant (BMT) is also called a stem cell transplant (SCT) or hematopoietic stem cell transplant (HSCT).The procedure replaces unhealthy blood-forming stem cells with healthy ones and offers some patients the possibility of a cure. But for many patients, a BMT is not an…
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Penn State Hershey Medical Center holds a
bone marrow
bone marrow:
The soft, spongy tissue inside most bones. Blood cells are formed in the bone marrow.
and stem cell transplant for BMT patients and their families to connect with each other and share experiences. For meeting information and for questions, please contact - (717) 531-0003, extension 281210.
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Penn State Hershey Medical Center holds a blood cancer support group for blood cancer patients and their families to connect with each other and share experiences. For meeting information and for questions, please contact - (800) 243-1455.
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We are pleased to let patients and families know about
bone marrow transplant
bone marrow transplant:
A bone marrow transplant (BMT) is also called a stem cell transplant (SCT) or hematopoietic stem cell transplant (HSCT).The procedure replaces unhealthy blood-forming stem cells with healthy ones and offers some patients the possibility of a cure. But for many patients, a BMT is not an…
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Cleveland Clinic holds a
bone marrow transplant
bone marrow transplant:
A bone marrow transplant (BMT) is also called a stem cell transplant (SCT) or hematopoietic stem cell transplant (HSCT).The procedure replaces unhealthy blood-forming stem cells with healthy ones and offers some patients the possibility of a cure. But for many patients, a BMT is not an option due…
support group…
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C.R. Wood Cancer Center holds a blood cancer support group on the second Wednesday of each month at 6:00pm. At the meetings, blood cancer patients and their families will connect with each other and share experiences. This group has both in-person and virtual attendance options. To register or for questions, please contact - Karen Cook, LMSW, at (518) 926-6619.
C.R. Wood Cancer Center
Pruyn…
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