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Research Articles

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Compiled for your convenience are articles on bone marrow failure research and treatment from the world’s major journals on hematology / oncology.

Article Title Original Publication Date Journal Bone Marrow Disease
Mutations in myelodysplastic syndromes: Core abnormalities and CHIPping away at the edges Aug 2020 International Journal of Laboratory Hematology Myelodysplastic Syndromes (MDS)
Myelodysplastic Syndromes: 2021 update on Diagnosis, Risk-stratification and Management Aug 2020 American Journal of Hematology Myelodysplastic Syndromes (MDS)
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes Aug 2020 Nature Medicine Myelodysplastic Syndromes (MDS)
High serum ferritin levels in newly diagnosed patients with myelodysplastic syndromes are associated with greater symptom severity Aug 2020 International Journal of Hematology Myelodysplastic Syndromes (MDS)
Safety and activity of selinexor in patients with myelodysplastic syndromes or oligoblastic acute myeloid leukaemia refractory to hypomethylating agents: a single-centre, single-arm, phase 2 trial Aug 2020 Lancet Hematology Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)
Patients with paroxysmal nocturnal hemoglobinuria demonstrate a prothrombotic clotting phenotype which is improved by complement inhibition with eculizumab Aug 2020 American Journal of Hematology Paroxysmal Nocturnal Hemoglobinuria (PNH)
Letter to the Editor: Allogeneic hematopoietic stem cell transplantation in elderly patients with acute myeloid leukemia or myelodysplastic syndromes: myth and reality Jul 2020 Leukemia Myelodysplastic Syndromes (MDS)
TP53 mutations in myelodysplastic syndromes and secondary AML confer an immunosuppressive phenotype Jul 2020 Blood Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)
Prognostic significance of serial molecular annotation in myelodysplastic syndromes (MDS) and secondary acute myeloid leukemia (sAML) Jul 2020 Leukemia Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)
HDAC4 inhibition disrupts TET2 function in high-risk MDS and AML Jul 2020 Aging Acute Myeloid Leukemia (AML), Myelodysplastic Syndromes (MDS)